Later, when the healthy cat goes to groom themselves, they ingest the contaminated saliva and then become infected. When an infected cat grooms a healthy cat, they leave their contaminated saliva on the fur. Another major form of spreading is grooming or fighting. The most common form of spreading is through saliva, as most multiple cat homes share food and water dishes. The virus is easily spread through direct contact between cats. FCoV can also be transmitted through different bodily fluids. The virus is shed in feces, and cats become infected by ingesting or inhaling the virus, usually by sharing cat litter trays, or by the use of contaminated litter scoops or brushes transmitting infected microscopic cat litter particles to uninfected kittens and cats. FCoV is common in places where large groups of cats are housed together indoors (such as breeding catteries, animal shelters, etc.). A study on 59 FIP infected cats found that, unlike FCoV, feces from FIP infected cats were not infectious to laboratory cats via oronasal route. There is a lack of evidence FIP is transmissible from cat to cat although it may explain rare mini-outbreaks of FIP.

However, many aspects of virus–host interactions affecting the disease remain uncertain, such as the factors that influence disease form (wet or dry), outcome (death or resistance), and host susceptibility. There is a general consensus that FIPVs arise from mutations enabling them to enter or replicate more successfully in monocytes (a type of white blood cell). From the gut, the virus very briefly undergoes a systemic phase, before returning to the gut where it is shed in the feces. The virus is a mutation of feline enteric coronavirus (FECV). Most infections are either asymptomatic or cause diarrhea, especially in kittens, as maternally derived antibody wanes at between 5 and 7 weeks of age. The virus and pathogenesis of FIP įCoV is a virus of the gastrointestinal tract. Usually fatal without treatment, but with GS-441524 treatment over 80% of treated cats make a full recovery.įeline infectious peritonitis ( FIP) is a common and aberrant immune response in cats to infection with feline coronavirus (FCoV). UK, Australia, Netherlands: GS-441524 (given orally as tablets) and its parent drug remdesivir (given by intravenous or subcutaneous injection) Keeping cats indoor to prevent the spread of feline coronavirus

Later on: ataxia, muscle weakness, dysphagia.Įnd phase: shortness of breath, urinary incontinence, paralysis.Ĭan take up to a year for symptoms to appear after exposure to virusġ-month or less average life expectancy after diagnosis, especially in kittens Initial phase: common cold-like symptoms. Medical condition Feline infectious peritonitisįIP-infected kidney showing inflammatory response

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